We have long struggled to determine how the first living organisms on Earth came together. Now, surprising evidence hints that poorly understood prions may have been the vital missing ingredient ...

As bispecifics, ADCs, protein degraders, and AI-designed mini-proteins move into the clinic, discovery teams face a new ...

Tryptophan, the essential amino acid behind the Thanksgiving myth that eating turkey can make you sleepy, has been found to ...

A team of researchers at IOCB Prague headed by Dr. Tomáš Slanina has developed a new method for labeling molecules with ...

This study investigates the folding and unfolding behavior of the doubly knotted protein TrmD-Tm1570, providing insight into the molecular mechanisms underlying protein knotting. The findings reveal ...

Traditional live attenuated vaccines (LAVs) are typically developed through serial passaging or genetic engineering to introduce specific mutations or deletions. While viral RNA secondary or tertiary ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. RNA possesses functional significance that extends beyond the transport of genetic ...

The application of deep learning algorithms in protein structure prediction has greatly influenced drug discovery and development. Accurate protein structures are crucial for understanding biological ...

Announcing a new publication for Acta Materia Medica journal. Proteins are essential macromolecules that perform functions according to their conformational dynamics. Studying the conformational ...

Tertiary Lymphoid Structures (TLS) correlate with positive outcomes in patients with NSCLC and the efficacy of immune checkpoint blockade (ICB) in cancer. The actin regulatory protein hMENA undergoes ...