Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, ...

The iSNP systems genomics pipeline models how non-coding SNPs cumulatively impact cellular signalling and gene regulatory networks, revealing patient-specific mechanisms linking disease-associated ...

Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may ...

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Neurodegenerative diseases, such as Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are medical conditions characterized by the progressive degradation ...

Mitochondrial DNA has long been treated as a workhorse record of cellular history, but new research suggests it also hides a subtle and previously overlooked form of damage. By uncovering this cryptic ...

The performance of skilled behaviors requires a balance between consistency and adaptability. Although the neural mechanisms that regulate this balance have been extensively studied at systems and ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

Under glaring laboratory lights, a research assistant extends his forearm and carefully inverts a mesh-topped container onto ...

DNA scaffolds that mirror influenza virus protein geometry boost antiviral binding and reduce infection more effectively than free molecules, enabling a modular antiviral design strategy.

EVE is a deep generative model combining evolutionary and human population data to estimate variant deleteriousness on a proteome-wide scale.