Disease development is often shaped by genetics, with how much or how little a gene is expressed influencing disease risk.

Using genomic and transcriptional data has greatly improved the understanding of multiple aspects of human physiology. A new paper in PNAS reports on molecular-level associations of co-occurring ...

This story is part of a series on the current progression in Regenerative Medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore tissues and organs damaged ...

Neurodegenerative diseases, such as Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and frontotemporal dementia ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the ...

“This suggests that longer-lived species may have evolved molecular programs that optimize splicing for longevity, allowing ...

New study links the APOE gene to increased delirium risk, independent of dementia, highlighting genetic factors in cognitive ...