Morning Overview on MSN

Hidden mitochondrial DNA damage may be a missing disease link

Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may ...
Morning Overview on MSN

Hidden mitochondrial DNA damage type uncovered by researchers

Mitochondrial DNA has long been treated as a workhorse record of cellular history, but new research suggests it also hides a subtle and previously overlooked form of damage. By uncovering this cryptic ...
C&EN

Plug-and-Play Approach for Preparing Chromatin Containing Site-Specific DNA Modifications: The Influence of Chromatin Structure on Base Excision Repair

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...
C&EN

Nucleotide Excision Repair and Impact of Site-Specific 5′,8-Cyclopurine and Bulky DNA Lesions on the Physical Properties of Nucleosomes

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Scientific Research Publishing

Selvakumaran, M., (2003) Enhanced Cisplatin Cytotoxicity by Disturbing the Nucleotide Excision Repair Pathway in Ovarian Cancer Cell Line. Cancer Research, 63, 1311-3116.

ABSTRACT: New chelates derived from the novel ligand, (Z)-3-amino-N-(3-amino pyrazine-2-carbonyl)pyrazine-2-carbohydrazonic acid (APA, L), with Cu2+, Co2+, Pt4+ and Pd2+ salts were investigated. The ...