Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may ...

Base excision repair is a process that removes and replaces damaged or misincorporated bases in one strand of the DNA that may generate mutations if left unrepaired. The damaged base is modified and ...

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

Mitochondrial DNA (mtDNA) exhibits a degree of resistance to mutagenesis under genotoxic stress, and this study on the mitochondrial Transcription Factor A (TFAM) presents valuable data concerning the ...