Urologic oncology has seen significant advances in precision therapy, with immunotherapy and organoid-based approaches at the forefront. Immunotherapy ...

The article reviews laser processing methods that enhance micro-LED displays, addressing optical challenges and improving ...

COLUMBUS—On November 17, the Polk County Board of Commissioners held its regular meeting at the Womack Building, located at 40 Courthouse Street. The meeting was marked by several key developments, ...

Aurigene’s A-PROX platform integrates library screening, direct-to-biology chemistries, proprietary ternary complex assays, modelling algorithms, and structure-based design to accelerate the discovery ...

PCAF (p300-associated factor), a major histone acetyltransferase, is involved in many metabolic and pathogenic diseases. Here, we reveal a novel function of PCAF in homologous recombination repair (HR ...

Identifying BRCAness in tumors, even in the absence of BRCA mutations, broadens the reach of targeted therapies, supporting more individualized and effective cancer treatment approaches. BRCAness ...

In patients unselected for homologous recombination repair (HRR) gene status, median overall survival (OS) improved from 37 months with the androgen receptor-pathway inhibitor (ARPI) alone to 45.8 ...

Divya Ramalingam Iyer, Naoya Harada, Connor Clairmont, Lige Jiang, David Martignetti, Huy Nguyen, Yizhou Joseph He, Dipanjan Chowdhury, Alan D. D’Andrea Proceedings of the National Academy of Sciences ...

Owning a car has plenty of benefits but also carries significant responsibilities. Keeping a car in good shape requires allocating funds toward routine car maintenance, as well as unexpected repairs.