RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Under the microscope, researchers often observe different cell types organizing themselves in peculiar patterns within tissues, or sometimes a rare cell type that stands out by occupying a unique ...

Philadelphia, June 1, 2023 – Researchers from Children’s Hospital of Philadelphia (CHOP) recently discovered that extremely thorough “deep sequencing” of the genome in tissue samples and cell-free DNA ...

Genomic landscapes of early-onset versus average-onset colorectal cancer populations. Evaluation of microsatellite instability status, a definitive predictive biomarker for immune checkpoint ...

Transcriptomic Predictors of Survival for Palbociclib + Endocrine Therapy Versus Capecitabine in Aromatase Inhibitor–Resistant Breast Cancer From the GEICAM/2013-02 PEARL Trial Our findings revealed a ...

A major puzzle of biology is that while the human genome contains roughly 20,000 genes, many comparatively primitive organisms — including the universally-studied worm C. elegans — have almost the ...

A new spatial transcriptomics technology—the DNA nanotechnology-driven method called “Light-Seq”—allows researchers to “geotag” the full repertoire of RNA sequences with unique DNA barcodes exclusive ...

Benefits of dual whole exome sequencing and gene-specific deep sequencing approach: • Novel variant analysis - Recently discovered gene variants, usually not covered by gene panel testing (100-900 ...

Please provide your email address to receive an email when new articles are posted on . DALLAS — Targeted sequencing appears to be a promising strategy for molecular profiling of head and neck ...

Genomics company Illumina (NASDAQ:ILMN) reported Q3 CY2025 results beating Wall Street’s revenue expectations , but sales were flat year on year at $1.08 billion. Its non-GAAP profit of $1.34 per ...