Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to separate ...
As chromosomes go, X and Y make an unlikely pair. The X is large and contains thousands of genes critical for life. The Y, by contrast, is little more than a nub. Its main purpose is to provide the ...
DSBs can be repaired using several different mechanisms. Both ends can be simply rejoined with little or no further processing (nonhomologous end joining, or NHEJ) or can be repaired using homologous ...
For decades, scientists believed that DNA strands under stress would form knots, tangling into chaotic shapes. But new research led by the University of Cambridge shows otherwise: when put under ...
Philosophical Transactions: Biological Sciences, Vol. 372, No. 1731, Theme issue: Chromatin modifiers and remodellers in DNA repair and signalling (5 October 2017), pp. 1-11 (11 pages) DNA double ...
Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to separate ...
One of the hallmarks of DNA damage is the rapid spreading of phosphorylated histone H2A (γ-H2AX) around a DNA double-strand break (DSB). In the budding yeast Saccharomyces cerevisiae, nearly all H2A ...
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