CURE

Sac-TMT Combo Shows Benefit in Advanced Lung Cancer Treatment

Sac-TMT combined with Keytruda significantly improves progression-free survival in PD-L1-positive advanced non-small cell ...

Kelun phase 3 ADC trial with Merck's Keytruda for NSCLC meets primary endpoint

Kelun Biotech's sac-TMT plus Merck's Keytruda shows significant progress in late-stage lung cancer trial. Read more here.
Fierce Pharma

Merck's partner Kelun touts phase 3 win for ADC-Keytruda combo in first-line lung cancer

With a phase 3 win for a combination of its TROP2-directed antibody-drug conjugate (ADC) sacituzumab tirumotecan (sac-TMT) ...
ZME Science on MSN

Painless Insulin? Skin Gel Sneaks Hormone Past the Body’s First Line of Defense

If you live with diabetes, your day is punctured by sharp little rituals: pens, syringes, infusion sets, or fingersticks. Now ...
BioSpace

Genmab Prunes Another ADC From $1.8B ProfoundBio Acquisition

Only one clinical-stage asset from the ProfoundBio acquisition remains in development: The antibody-drug conjugate Rina-S, in ...
The EMBO Journal

Flagellar rotation facilitates the transfer of a bacterial conjugative plasmid

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Conjugation-mediated DNA delivery is the ...
SciELO

Enhancing the Transgene Performance of Polyethyleneimine through Amino Acid Conjugation

The delivery of nucleic acids requires a gene vector as they are unable to effectively cross cell membranes. Polycations and deoxyribonucleic acid (DNA) can self-assemble into polyplexes enabling ...
PR Newswire

Acepodia Enters Strategic Clinical Collaboration with Pfizer to Accelerate Development of Antibody-Cell Conjugation-Based Cell Therapies in Autoimmune Diseases

Through Pfizer Ignite, Acepodia will gain access to Pfizer's resources, scale and expertise as the company broadens the application of its platform beyond oncology into autoimmune diseases Pfizer ...