Using genomic and transcriptional data has greatly improved the understanding of multiple aspects of human physiology. A new paper in PNAS reports on molecular-level associations of co-occurring ...
Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the ...
Neurodegenerative diseases, such as Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and frontotemporal dementia ...
This story is part of a series on the current progression in Regenerative Medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore tissues and organs damaged ...
“This suggests that longer-lived species may have evolved molecular programs that optimize splicing for longevity, allowing ...
When a gene is expressed, its DNA sequence is transcribed into a molecule known as RNA. Then the cell processes and edits ...
Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...
For decades, biologists treated DNA as a static string of letters, a linear code that cells read like text on a page. A new ...
New study links the APOE gene to increased delirium risk, independent of dementia, highlighting genetic factors in cognitive ...