The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins -- yet it exists in large quantities. A research team has ...

Gene expression analysis is undergoing a profound transformation, driven by the rapid evolution of advanced omics technologies. From single-cell ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

The function of a protein can depend on its abundance in a cell. So, when investigating the properties of a new protein, it is essential to make sure that the same amount is produced by every cell.

Following surgery, patients with breast cancer are faced with the question of whether additional chemotherapy is necessary and really effective. It is important that these women do not receive too ...

The goal of gene therapy for patients with hemophilia A is to safely impart long-term stable factor VIII expression that predictably ameliorates bleeding with the use of the lowest possible vector ...

As gene therapies continue to advance, the demand for scalable, reproducible, and efficient potency assays is rapidly increasing—especially for adeno-associated virus (AAV) vectors. Accurate ...

A large class of mammalian genes is not completely shared throughout sperm development and differentiation, according to a new study of sperm in organisms including mice, macaques and men. The ...

As the days continue to get shorter, scientists have made a significant discovery in understanding exactly what makes mammals ...