RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Under the microscope, researchers often observe different cell types organizing themselves in peculiar patterns within tissues, or sometimes a rare cell type that stands out by occupying a unique ...

Transcriptomic Predictors of Survival for Palbociclib + Endocrine Therapy Versus Capecitabine in Aromatase Inhibitor–Resistant Breast Cancer From the GEICAM/2013-02 PEARL Trial Our findings revealed a ...

Philadelphia, June 1, 2023 – Researchers from Children’s Hospital of Philadelphia (CHOP) recently discovered that extremely thorough “deep sequencing” of the genome in tissue samples and cell-free DNA ...

Genomic landscapes of early-onset versus average-onset colorectal cancer populations. Evaluation of microsatellite instability status, a definitive predictive biomarker for immune checkpoint ...

Please provide your email address to receive an email when new articles are posted on . DALLAS — Targeted sequencing appears to be a promising strategy for molecular profiling of head and neck ...

A major puzzle of biology is that while the human genome contains roughly 20,000 genes, many comparatively primitive organisms — including the universally-studied worm C. elegans — have almost the ...

Benefits of dual whole exome sequencing and gene-specific deep sequencing approach: • Novel variant analysis - Recently discovered gene variants, usually not covered by gene panel testing (100-900 ...

Marine sediments cover more than two thirds of our planet's surface. Nevertheless, they are scarcely explored, especially in the deeper regions of the oceans. For their nutrition, the bacteria in the ...