Proteins that bind to DNA are ubiquitous in biology. The ability of these proteins to bind to specific DNA sequences with high affinity is often central to their function, and it is not uncommon for a ...

Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to separate ...

DSBs can be repaired using several different mechanisms. Both ends can be simply rejoined with little or no further processing (nonhomologous end joining, or NHEJ) or can be repaired using homologous ...

University of Hull provides funding as a member of The Conversation UK. DNA (which stands for deoxyribonucleic acid) contains all the information needed to make your body work. It is also surprisingly ...

The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...

One of the hallmarks of DNA damage is the rapid spreading of phosphorylated histone H2A (γ-H2AX) around a DNA double-strand break (DSB). In the budding yeast Saccharomyces cerevisiae, nearly all H2A ...

A recent study in Nature Plants examined the genetic regulation of endosymbiotic gene transfer (EGT) in plants. Researchers found that deoxyribonucleic acid (DNA) double-strand break repair (DSBR) ...